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they get the crap beat out of them and break down pretty fast... i imagine at some point a person would get tired of it, or get too old for it. speed, strength, and reaction time gets worse too as you age, and i imagine they're more important for RBs then just about anyone else...
or maybe all the knocks just does something to them... I mean, if mike tyson hit my head twice i'm sure i wouldn't be thinking straight for very long...
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