First, this is a great idea to post! Especially since I seem to get about 10 colds a year, at least when I lived in Nashville. My remedy recently has been pretty much just like GMScud's....Zicam as soon as I feel funny (I like the nasal swabs), Nyquil liquid at night (if it looks like it's getting bad), and drink liquids all day....water, gatorade, tea, and maybe a couple of red bull and vodka's